In a future to come humanity enjoys a new age of prosperity thanks to Dr. Shizuma's invention of a revolutionary renewable energy source: the Shizuma Drive. But this peace is threatened by Big Fire, a cabal seeking world domination. Against Big Fire the International Police Organisation dispatches a collection of superpowered warriors and martial artists, together with Daisaku Kusama, inheritor and master of Earth's most powerful robot, Giant Robo. By capturing an abnormal Shizuma Drive which is essential to Big Fire's plans the IPO ignites a desperate conflict between the two groups. The coming battle will test Daisaku's resolve to the utmost, reveal the ghastly truth behind the creation of the Shizuma Drive, and bring human civilization to its knees! Giant Robo is a character-driven adventure in a retro-futuristic setting, drawing on influences from opera, kung-fu cinema, wuxia stories and classic mecha anime. It incorporates characters from the works of the manga author Mitsuteru Yokoyama but it is designed to be a stand-alone story.

Following the awakening of her Dream-Sight ability, Miyo Saimori reunites with her fiancé, Kiyoka Kudou, the captain of the special forces protecting the country against ill-intended individuals gifted with exceptional powers. However, the couple's blissful life is suddenly interrupted when Takaihito, the top contender for the imperial throne, sends Kiyoka on a dangerous mission. Traveling with Miyo to the remote household of his parents, Kiyoka must investigate unusual reports of demons in the region. Meanwhile, Miyo tries to gain the approbation of her callous mother-in-law, Fuyu, who refuses to recognize her as a family member. After Kiyoka repels an attack by the Gifted Communion, a subversive sect of special abilities wielders, he returns to the capital alongside his fiancée. As the looming threat against the imperial authority intensifies, Kiyoka must thwart the Gifted Communion's plans to protect Miyo and everyone he holds dear.

After human experimentation turns Kisaragi into a cyborg, he finds himself pressured by multiple organizations: An undying convent of vampires bent on the conquest of Tokyo, and an immortal order of knights, and a group of Yakuza, sword to avenge the killing of their leader. "I might not have any reason to live, but that's no reason to let them kill me." Kisaragi will have to use his cyborg-body and his unique "blood," as well as anything else he can to make his big escape!!!

Sequel to Uchuu Senkan Yamato 2205: Aratanaru Tabidachi.